Cancer Support Group

Monday, Nov 20th

Last update:06:42:40 AM GMT

Home Cancer Chemotherapy Chemotherapy Do We Need to Worry?

Chemotherapy Do We Need to Worry?

Combination Chemotherapy

Development of Resistance with Single and Multiple Drug Treatment
Development of Resistance with Single and Multiple Drug Treatment


Principles of Combination Therapy
  • Drugs known to be active as single agents.
  • Drugs with different mechanisms of action.
  • Drugs with differing dose limiting toxicities.
  • Drugs should be used in optimal dose and schedule.
  • Drugs given at constant intervals.
  • Drugs with different patterns of resistance.

Tumour Kinetics

Tumour and Normal Cell Growth Kinetics
Tumour and Normal Cell Growth Kinetics


The Cell Cycle
There are 3 Cell Populations in a Tumour
  • Dividing (Cycling).
  • Resting (Dormant).
  • Differentiating.
Dividing Cells May be
  • G1 - RNA/Protein Synthesis.
  • S - Dna Synthesis.
  • G2 - Pre Mitosis.
  • M - Mitosis.
  • G0 - Resting.

The Cell Cycle
The Cell Cycle


Suggestions

This is YOUR sites, so if you have suggestions or feedback on how we can improve it for you, please let us know! We do our best to keep up!

Make a Suggestion
Manthan Award

Link to Aarogya

aarogya logo
NASSCOM Award