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Home News and Update Year 2010 Drug To Cut Cancer Therapy Side-effects

Drug To Cut Cancer Therapy Side-effects

Times of India
18 September 2010
By Shimona Kanwar
Chandigarh, India

DRDO Pill Will Reduce Hair Loss By 75%
Cancer patients undergoing radiotherapy have to cope with some side–effects, including hair–loss. They have a hope: a drug, developed by Defence Research & Development Organization (DRDO), promises to reduce these side–effects by 75%. It will soon be available in the market.

Drug To Cut Cancer Therapy Side-effects
The drug, 2–deoxy–D–glucose (2–DG) has completed three phases of clinical trials and has been sent to a Hyderabad–based laboratory for commercial production pending final approval from the Directorate General of Health Services.

At present there is no drug available that can reduce the side–effects of radiotherapy. If the drug is given to any cancer patient before radiotherapy, the side–effects such as hairfall, nausea, loss of appetite and sleeplessness can be substantially reduced. The multi–centric trials had been carried out in eight cancer hospitals and research institutes.

W Selvamurthy, chief controller (R&D), DRDO said: "The drug has been tested on adult malignant cancer patients with success and it has been patented."

The drug is an analogue of glucose which is structurally same as the blood glucose cells in a human body. The cancer cells are hyperactive as they proliferate rapidly and feed on glucose cells in the body, thus depriving the body of its immunity and energy level.

Selvamurthy explained: "These cancer cells start eating the analogue glucose, which does not provide energy like the real glucose cells in the blood. Consequently, it weakens the cancer cells. The radiation from the radiotherapy then destroys these weak cells easily without affecting the surrounding normal cells in the body."

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