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Home News and Update Year 2011 Now, Bloodless Transplant of Bone Marrow

Now, Bloodless Transplant of Bone Marrow

Times of India
19 February 2011
Ahmedabad, India

Instead of the conventional Bone Marrow Transplant (BMT), where the patient is given an average 15 transfusions of platelet, a blood component, a bloodless BMT was performed recently where the patient was not given any blood of other person.

Medical oncologist at HCGMedisurge Dr Radheshyam saidthattheBMTon 60–year–old Curtis Carpenter from the US was the first bloodless BMT performed in Asia. Carpenter suffered from the non–Hodgkin’s lymphoma and underwent chemotherapy in the US. Later, he visited Banglore for treatment.

Since Carpenter was a follower of Jehovah’s Witness community, he refused blood transfusion. "People who belong to this community are averse to taking blood transfusions. Bloodless BMT is carried out only at one centre in the US. We decided to go ahead with the procedure as the patient did not give us any option," Dr Radheshyam told TOI on his visit to the city on Friday.

Conventionally, stem cells are collected from the patient’s peripheralblood and preserved. The patient is then given high dose of chemotherapy to kill all blood cells including the cancer cells. The stem cells are then infused.

The bone marrow, however, takes a few weeks to recover. During this period, blood components like platelets and red blood cells are given to the patientsto preventthem from falling prey to infections and acutely low haemoglobin.

"Since giving blood components was not an option, we ensured that the patient had high haemoglobin levels pre–procedure. Also, we aggressively treatedonsetof fever andinfections as these incidents use up more platelets if allowed to spike. We also used a specific drug which helped the patient," said Dr Radheshyam.
The surgery, which costs Rs 85 lakh in the US, cost Carpenter Rs 15 lakh in India.

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